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Tridecapeptide-1 Concentrate Intensive Skin Repair

Products Name Tridecapeptide-1
INCI Name Tridecapeptide-1
Specification ≥95% (HPLC)
Molecular Weight ~1300-1400 g/mol 
Chemical Formula Custom peptide sequence (C₅₈H₉₂N₁₈O₁₉ range)
Appearance White to off-white lyophilized powder
Solubility Soluble in water
    Gamma-Oryzanol (4)
    01

    Product Description

    1. Mechanism of Action (MOA)
    Tridecapeptide-1 is a sophisticated long-chain peptide engineered to target multiple pathways of skin aging through comprehensive biomimetic action:

    Extracellular Matrix Synthesis
    Stimulates collagen I, III, IV and VII production
    Enhances elastin and fibronectin synthesis
    Activates multiple growth factor pathways
    Cellular Communication
    Modulates integrin-mediated signaling
    Promotes fibroblast-keratinocyte interaction
    Supports stem cell activity and regeneration

    Protective Functions
    Reduces MMP-1, MMP-3, MMP-9 activity
    Enhances antioxidant defense systems
    Strengthens dermal-epidermal junction

    2. In Vitro Efficacy Data
    Collagen Synthesis Studies
    198% increase in collagen I production
    156% enhancement in collagen III synthesis
    124% upregulation in elastin expression

    Cellular Function Analysis
    2.8-fold improvement in fibroblast proliferation
    82% enhancement in cell migration capacity
    Significant reduction in cellular senescence markers

    Protective Effects
    73% reduction in MMP-1 activity
    85% decrease in oxidative stress
    Enhanced DNA repair mechanisms

    3. Clinical Results
    28-84 day clinical studies demonstrate:

    Wrinkle Improvement
    47% reduction in wrinkle depth
    52% improvement in skin smoothness
    45% enhancement in skin elasticity

    Skin Quality Parameters
    68% increase in skin density
    57% improvement in skin firmness
    91% of subjects reported improved skin radiance

    Overall Results
    96% satisfaction with anti-aging effects
    93% reported visibly younger-looking skin
    Significant improvement in skin texture and tone


    Safety & Compatibility

    Thickeners

    Safety Profile

    *Non-irritating (HRIPT confirmed) *Non-sensitizing at recommended concentrations *Suitable for all skin types including sensitive skin
    Actives

    Formulation Compatibility

    *PH stability range: 4.0-7.5
    *Compatible with common cosmetic ingredients: Hyaluronic acid and derivatives
    Vitamin C, E and derivatives
    Niacinamide
    Other peptide complexes
    Botanical extracts and oils
    Gamma-Oryzanol (4)
    01

    Recommended Usage & Formulations

    Optimal Concentration: 2-5%

    Preferred Formulations
    Anti-aging serums and concentrates
    Firming and lifting creams
    Neck and décolletage treatments
    Intensive repair ampoules
    O/W and W/O emulsions

    Application Frequency
    Twice daily for optimal results
    Suitable for long-term continuous use

    Summary & Key Selling Points

    Applications1
    01

    Advanced Multi-Target Technology

    *Comprehensive approach to skin rejuvenation *Addresses multiple aging pathways simultaneously
    Applications3
    01

    Clinically Proven Efficacy

    *Significant reduction in wrinkle depth and severity *Improved skin density, firmness and elasticity *Enhanced skin radiance and texture
    Applications5
    03

    Superior Safety Profile

    *Excellent tolerance across all skin types *Broad formulation compatibility
    Applications5
    03

    Market Differentiation

    *Advanced long-chain peptide technology *Strong scientific evidence base *Premium anti-aging positioning
    storage

    Storage

    Store in a closed container at a dry place at room temperature.

    gmo1

    Animal Testing

    Not animal tested

    vegetarian1

    Vegan

    Does not contain animal-derived components

    gmo

    GMO

    No data available

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